MCM5 抗体 (N-Term)
Quick Overview for MCM5 抗体 (N-Term) (ABIN2774889)
抗原
See all MCM5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- MSGFDDPGIF YSDSFGGDAQ ADEGQARKSQ LQRRFKEFLR QYRVGTDRTG
-
预测反应
- Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%
-
产品特性
- This is a rabbit polyclonal antibody against MCM5. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MCM5
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 734 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
-
别名
- MCM5
-
背景
-
The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Alias Symbols: CDC46, P1-CDC46
Protein Interaction Partner: KRTAP10-7, RBPMS, SUMO2, SUMO3, MCMBP, UBC, RNF2, NEK9, MCM3, HSP90AB1, HSP90AA1, FKBP5, MAGED2, CAP1, BAG3, CD81, IGSF8, TCEA1, PNKP, VCAM1, ORC5, ORC1, MCM7, MCM2, ITGA4, FN1, CDKN2A, CDC5L, NOTCH1, MYBBP1A, U2AF1, MCM6, MCM4, HNRNPU, APP, FBXO6, NEDD8,
Protein Size: 734 -
分子量
- 82 kDa
-
基因ID
- 4174
-
NCBI登录号
- NM_006739, NP_006730
-
UniProt
- P33992
-
途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
-