SYVN1 抗体 (C-Term)
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北京 101111
Quick Overview for SYVN1 抗体 (C-Term) (ABIN2774801)
抗原
See all SYVN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SYVN1 Antibody - C-terminal region
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序列
- ARLQSLRNIH TLLDAAMLQI NQYLTVLASL GPPRPATSVN STEETATTVV
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预测反应
- Cow: 85%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SYVN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SYVN1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113265
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
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别名
- SYVN1
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背景
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Background Information: SYVN1 is a protein involved in endoplasmic reticulum (ER)-associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.
Gene Name: Synovial apoptosis inhibitor 1, synoviolin
Alternative Symbols: DER3, HRD1
Protein Name: E3 ubiquitin-protein ligase synoviolin
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分子量
- 67kDa
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基因ID
- 84447
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NCBI登录号
- NP_115807
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UniProt
- Q86TM6
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途径
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
抗原
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