ITCH 抗体 (N-Term)
Quick Overview for ITCH 抗体 (N-Term) (ABIN2774796)
抗原
See all ITCH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QLESEVVTNG ETTCSESASQ NDDGSRSKDE TRVSTNGSDD PEDAGAGENR
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预测反应
- Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against ITCH. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ITCH
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 862 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
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别名
- ITCH
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背景
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Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot
Alias Symbols: AIF4, AIP4, NAPP1, dJ468O1.1
Protein Interaction Partner: GSN, UBE2L3, UBC, ITCH, WWOX, GGA3, UBE2D2, PTCH1, ATXN3, HTT, EGFR, SMAD6, DTX3L, CXCR4, LATS1, POLR2A, HNRNPL, EWSR1, RPAP2, CPSF7, RPAP3, UBAP2, PABPC1, DAZAP1, WBP2, SMARCE1, SMARCC2, SMARCC1, POLR2E, POLR2C, SPG20, HNRNPUL1, UBAP2L, URI1, ARID1A, SF1
Protein Size: 862 -
分子量
- 99 kDa
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基因ID
- 83737
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NCBI登录号
- NM_031483, NP_113671
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UniProt
- A9Z1X3
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途径
- Activation of Innate immune Response, CXCR4-mediated Signaling Events
抗原
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