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ITCH 抗体 (N-Term)

This anti-ITCH antibody is a 兔 多克隆 antibody detecting ITCH in WB. Suitable for 人, 大鼠, Cow, 兔, 犬, 马 和 豚鼠.
产品编号 ABIN2774796
发货至: 中国
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Quick Overview for ITCH 抗体 (N-Term) (ABIN2774796)

抗原

See all ITCH 抗体
ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

适用

  • 53
  • 44
  • 21
  • 2
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  • 1
人, 大鼠, Cow, 兔, 犬, 马, 豚鼠

宿主

  • 55
  • 4
  • 1

克隆类型

  • 43
  • 17
多克隆

标记

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  • 5
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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This ITCH antibody is un-conjugated

应用范围

  • 43
  • 31
  • 20
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  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 11
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    QLESEVVTNG ETTCSESASQ NDDGSRSKDE TRVSTNGSDD PEDAGAGENR

    预测反应

    Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against ITCH. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ITCH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 862 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

    别名

    ITCH

    背景

    Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot
    Alias Symbols: AIF4, AIP4, NAPP1, dJ468O1.1
    Protein Interaction Partner: GSN, UBE2L3, UBC, ITCH, WWOX, GGA3, UBE2D2, PTCH1, ATXN3, HTT, EGFR, SMAD6, DTX3L, CXCR4, LATS1, POLR2A, HNRNPL, EWSR1, RPAP2, CPSF7, RPAP3, UBAP2, PABPC1, DAZAP1, WBP2, SMARCE1, SMARCC2, SMARCC1, POLR2E, POLR2C, SPG20, HNRNPUL1, UBAP2L, URI1, ARID1A, SF1
    Protein Size: 862

    分子量

    99 kDa

    基因ID

    83737

    NCBI登录号

    NM_031483, NP_113671

    UniProt

    A9Z1X3

    途径

    Activation of Innate immune Response, CXCR4-mediated Signaling Events
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