HERC5 抗体 (N-Term)
Quick Overview for HERC5 抗体 (N-Term) (ABIN2774738)
抗原
See all HERC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- CLVAELVGYR VTQIACGRWH TLAYVSDLGK VFSFGSGKDG QLGNGGTRDQ
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预测反应
- Cow: 86%, Dog: 79%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against HERC5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HERC5
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anti-Hect Domain and RLD 5 (HERC5) (Middle Region) antibody
HERC5 适用: 人, Cow, 马, 兔, 大鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 153-284) antibodyHERC5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 915-1024) antibodyHERC5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 287-336) antibodyHERC5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 900-949) antibodyHERC5 适用: 人, Cow, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 360-700) antibodyHERC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (N-Term) antibodyHERC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1024 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HERC5 (Hect Domain and RLD 5 (HERC5))
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别名
- HERC5
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背景
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HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Alias Symbols: CEB1, CEBP1
Protein Interaction Partner: UBC, SMAD4, UBE2D1, gag, ISG15, TXNRD1, IRF3, HSPA8, CTNNB1, HERC5, SIRT7, STK38, PITX2, ERCC2, CCND1, CCNE1, CCNB1, CCNA2, NME2, CDKN1A,
Protein Size: 1024 -
分子量
- 117 kDa
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基因ID
- 51191
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NCBI登录号
- NM_016323, NP_057407
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UniProt
- Q9UII4
抗原
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