EIF2AK2 抗体 (Middle Region)
Quick Overview for EIF2AK2 抗体 (Middle Region) (ABIN2774645)
抗原
See all EIF2AK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QVFKAKHRID GKTYVIKRVK YNNEKAEREV KALAKLDHVN IVHYNGCWDG
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预测反应
- Cow: 92%, Dog: 83%, Horse: 91%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against EIF2AK2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human EIF2AK2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 551 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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别名
- EIF2AK2
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背景
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EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Alias Symbols: EIF2AK1, MGC126524, PKR, PRKR
Protein Interaction Partner: UBC, TRAF6, TRAF5, TRAF2, EGFR, DHX9, STAU2, PRKRA, EIF2AK2, HECW2, TOP1, STAU1, DICER1, DHX30, EBNA1BP2, IGF2BP2, IGF2BP3, PABPC4, MOV10, ILF3, ILF2, HSP90AA1, EIF2A, NOC3L, GNL3, NOP2, HNRNPC, HIST1H1C, ELAVL1, NPM1, IL7R, gag, Jak2, TYK2, JAK1, EIF2S1,
Protein Size: 551 -
分子量
- 62 kDa
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基因ID
- 5610
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NCBI登录号
- NM_002759, NP_002750
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UniProt
- P19525
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途径
- DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C
抗原
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