SETMAR 抗体 (C-Term)
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Quick Overview for SETMAR 抗体 (C-Term) (ABIN2773983)
抗原
See all SETMAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FLQGKRFHNQ QDAENAFQEF VESQSTDFYA TGINQLISRW QKCVDCNGSY
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预测反应
- Cow: 100%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against SETMAR. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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别名
- SETMAR
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背景
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This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.
Protein Interaction Partner: CHEK1, H3F3C, tat, PRPF19, SETMAR, RAD9A, PCNA, TOP2A, XRCC4,
Protein Size: 545 -
分子量
- 59 kDa
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基因ID
- 6419
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NCBI登录号
- NP_001230652
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UniProt
- E7EN68
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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