PVRL2 抗体
(1 reference)Quick Overview for PVRL2 抗体 (ABIN2749202)
抗原
See all PVRL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD112 Purified
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特异性
- The mouse monoclonal antibody R2.525 recognizes an extracellular epitope on CD112, a type I transmembrane glycoprotein expressed by myelomonocytic and megakaryocytic cells, and by CD34+ hematopoietic progenitors.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- NIH/3T3 cells transfected with human Nectin-2
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亚型
- IgG1 kappa
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anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 76-353) antibody
PVRL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) antibodyPVRL2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A6-2C1 unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 58-212) antibodyPVRL2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4A11B12 unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 251-350) antibodyPVRL2 适用: 人 WB, FACS, ELISA, ICC, IF (p), IHC (fro), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 83-291) antibodyPVRL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) antibodyPVRL2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) antibody (PE)PVRL2 适用: 人 FACS 宿主: 小鼠 Monoclonal R2-525 PE
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) antibodyPVRL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) antibodyPVRL2 适用: 人 FACS, ELISA, IP 宿主: 小鼠 Monoclonal B-C12 unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 148-161), (Extracellular) antibodyPVRL2 适用: 小鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 6969-77, (2014) (PubMed).
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: "CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 6969-77, (2014) (PubMed).
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- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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别名
- CD112
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背景
- Nectin cell adhesion molecule 2,CD112, also known as nectin-2, is a transmembrane glycoprotein involved in organization of adherens junctions. It also serves as a target molecule for entry of certain strains of herpes simplex virus (HSV) and pseudorabies virus (PRV). It is homologous to CD155, which serves as a target molecule for polio virus. CD112 seems to play a role in neural tube formation, with N-cadherin. Inside the cell, CD112 is connected with actin cytoskeleton through afadin. Variations in the CD112 gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,NECTIN2, HVEB, PRR2, PVRL2, PVRR2
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基因ID
- 5819
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UniProt
- Q92692
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
抗原
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