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SLAMF1 抗体 (FITC)

This anti-SLAMF1 antibody is a 小鼠 单克隆 antibody detecting SLAMF1 in FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2749108
发货至: 中国

Quick Overview for SLAMF1 抗体 (FITC) (ABIN2749108)

抗原

See all SLAMF1 抗体
SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SLAMF1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

SLAM-4
  • 原理

    Anti-Hu CD150 FITC

    特异性

    The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human CD150-transfected 300.19 cells

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

    Romero, Benítez, March, Vilella, Miralpeix, Engel: "Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)." in: Tissue antigens, Vol. 64, Issue 2, pp. 132-44, (2004) (PubMed).

  • 抗原

    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

    别名

    CD150

    背景

    Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1

    基因ID

    6504

    UniProt

    Q13291
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