电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MERTK 抗体 (N-Term)

Cited in 9+ publications. This 兔 多克隆 anti-MERTK antibody specifically detects MERTK in WB, IHC, ELISA, IP, IF, ICC 和 CM. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2746860
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MERTK 抗体 (N-Term) (ABIN2746860)

抗原

See all MERTK 抗体
MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

适用

  • 113
  • 39
  • 27
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 91
  • 26
  • 4
  • 2
  • 1

克隆类型

  • 63
  • 61
多克隆

标记

  • 64
  • 11
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MERTK antibody is un-conjugated

应用范围

  • 74
  • 62
  • 51
  • 19
  • 14
  • 14
  • 12
  • 9
  • 8
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)
  • 抗原表位

    • 13
    • 12
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide corresponding to unique amino acid sequence on MerTK protein.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.75 μg/μL
  • Ginisty, Gély-Pernot, Abaamrane, Morel, Arnault, Coronas, Benzakour: "Evidence for a subventricular zone neural stem cell phagocytic activity stimulated by the vitamin K-dependent factor protein S." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 515-25, (2015) (PubMed).

    Farkas, Lew, Sousa, Bujakowska, Chatagnon, Bhattacharya, Pierce, Nandrot: "Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium." in: The American journal of pathology, Vol. 184, Issue 10, pp. 2641-52, (2014) (PubMed).

    Fraineau, Monvoisin, Clarhaut, Talbot, Simonneau, Kanthou, Kanse, Philippe, Benzakour: "The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner." in: Blood, Vol. 120, Issue 25, pp. 5073-83, (2013) (PubMed).

    Choi, Park, Lee, Byun, Youn, Choi, Woo, Kang: "Upregulation of Mer receptor tyrosine kinase signaling attenuated lipopolysaccharide-induced lung inflammation." in: The Journal of pharmacology and experimental therapeutics, Vol. 344, Issue 2, pp. 447-58, (2013) (PubMed).

    Qin, Rodrigues: "Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis." in: Experimental eye research, Vol. 94, Issue 1, pp. 63-70, (2012) (PubMed).

    Lee, Han, Byun, Park, Park, Chong, Cho, Kang: "Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-κB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury." in: Journal of leukocyte biology, Vol. 91, Issue 6, pp. 921-32, (2012) (PubMed).

    Caberoy, Zhou, Li: "Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis." in: The EMBO journal, Vol. 29, Issue 23, pp. 3898-910, (2011) (PubMed).

    Tibrewal, Wu, Dmello, Akakura, George, Varnum, Birge: "Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3618-27, (2008) (PubMed).

    Wu, Singh, Georgescu, Birge: "A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells." in: Journal of cell science, Vol. 118, Issue Pt 3, pp. 539-53, (2005) (PubMed).

  • 抗原

    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

    别名

    MERTK

    UniProt

    Q12866

    途径

    RTK signaling
You are here: