电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MERTK 抗体 (N-Term)

This anti-MERTK antibody is a 兔 多克隆 antibody detecting MERTK in WB, IHC, ELISA, IF, ICC, IP 和 CM. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 9+ publications.
产品编号 ABIN2746860
发货至: 中国

Quick Overview for MERTK 抗体 (N-Term) (ABIN2746860)

抗原

See all MERTK 抗体
MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

适用

  • 94
  • 36
  • 25
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 67
  • 32
  • 2
  • 2
  • 1

克隆类型

  • 59
  • 45
多克隆

标记

  • 58
  • 10
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This MERTK antibody is un-conjugated

应用范围

  • 54
  • 51
  • 45
  • 20
  • 14
  • 13
  • 12
  • 11
  • 8
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Confocal Microscopy (CM)
  • 抗原表位

    • 23
    • 13
    • 8
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide corresponding to unique amino acid sequence on MerTK protein.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.75 μg/μL
  • Ginisty, Gély-Pernot, Abaamrane, Morel, Arnault, Coronas, Benzakour: "Evidence for a subventricular zone neural stem cell phagocytic activity stimulated by the vitamin K-dependent factor protein S." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 515-25, (2015) (PubMed).

    Farkas, Lew, Sousa, Bujakowska, Chatagnon, Bhattacharya, Pierce, Nandrot: "Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium." in: The American journal of pathology, Vol. 184, Issue 10, pp. 2641-52, (2014) (PubMed).

    Fraineau, Monvoisin, Clarhaut, Talbot, Simonneau, Kanthou, Kanse, Philippe, Benzakour: "The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner." in: Blood, Vol. 120, Issue 25, pp. 5073-83, (2013) (PubMed).

    Choi, Park, Lee, Byun, Youn, Choi, Woo, Kang: "Upregulation of Mer receptor tyrosine kinase signaling attenuated lipopolysaccharide-induced lung inflammation." in: The Journal of pharmacology and experimental therapeutics, Vol. 344, Issue 2, pp. 447-58, (2013) (PubMed).

    Qin, Rodrigues: "Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis." in: Experimental eye research, Vol. 94, Issue 1, pp. 63-70, (2012) (PubMed).

    Lee, Han, Byun, Park, Park, Chong, Cho, Kang: "Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-κB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury." in: Journal of leukocyte biology, Vol. 91, Issue 6, pp. 921-32, (2012) (PubMed).

    Caberoy, Zhou, Li: "Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis." in: The EMBO journal, Vol. 29, Issue 23, pp. 3898-910, (2011) (PubMed).

    Tibrewal, Wu, Dmello, Akakura, George, Varnum, Birge: "Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3618-27, (2008) (PubMed).

    Wu, Singh, Georgescu, Birge: "A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells." in: Journal of cell science, Vol. 118, Issue Pt 3, pp. 539-53, (2005) (PubMed).

  • 抗原

    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

    别名

    MERTK

    UniProt

    Q12866

    途径

    RTK signaling
You are here:
Chat with us!