SUMO1 抗体
Quick Overview for SUMO1 抗体 (ABIN2744595)
抗原
See all SUMO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human SUMO1 / SMT3
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纯化方法
- Protein G purified
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免疫原
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Recombinant human SUMO1 protein.
Type of Immunogen: Recombinant protein -
亚型
- IgG1 kappa
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应用备注
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody is specific to SUMO1 and shows no cross-reaction with either SUMO2 or SUMO3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO1 protein localizes to the nuclear membrane. ELISA: Order BSA-free format for coating. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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别名
- SUMO1 / SMT3
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背景
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Name/Gene ID: SUMO1
Synonyms: SUMO1, GAP modifying protein 1, GMP1, OFC10, Sentrin, SMT3 homolog 3, SMT3C, SMT3H3, SUMO-1, Ubiquitin-like protein UBL1, PIC1, Ubiquitin-like 1 (sentrin), UBL1, DAP1, GAP-modifying protein 1, Ubiquitin-like protein SMT3C -
基因ID
- 7341
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途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
抗原
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