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CD31 抗体

This anti-CD31 antibody is a 小鼠 单克隆 antibody detecting CD31 in FACS, WB, IHC, IF, ELISA, IP 和 IHC (p). Suitable for 人, 兔 和 Cynomolgus.
产品编号 ABIN2743591
发货至: 中国

Quick Overview for CD31 抗体 (ABIN2743591)

抗原

See all CD31 (PECAM1) 抗体
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

适用

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人, 兔, Cynomolgus

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD31 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

C31-7
  • 特异性

    Human PECAM-1 / CD31

    纯化方法

    Protein G purified

    免疫原

    Human recombinant PECAM-1 / CD31 protein.

    Type of Immunogen: Recombinant protein

    亚型

    IgG1 kappa
  • 应用备注

    Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: PECAM-1, or platelet endothelial cell adhesion molecule-1, also called CD31, is made up of six extracellular immunoglobulin-like domains, a single transmembrane domain, and a cytoplasmic domain containing serine and tyrosine residues that when phosphorylated, activate the molecules signaling function. It is expressed on platelets, monocytes, neutrophils, bone marrow macrophage and dendritic cells precursors, and at the intracellular junction of endothelial cells. PECAM-1, on the endothelial lining of blood vessels, helps maintain the vascular barrier. In response to inflammatory mediators, the endothelial pull away from each other allowing fluid, inflammatory cells and proteins into the extravascular space. The inflammatory response fades as adhesion of neighboring cells increase. PECAM-1 also plays an important role in angiogenesis, promoting endothelial cell motility, junctional development and capillary morphogenesis. ELISA: Order BSA-free format for coating.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    别名

    PECAM-1 / CD31

    背景

    Name/Gene ID: PECAM1

    Synonyms: PECAM1, CD31, CD31 antigen, EndoCAM, PECA1, PECAM-1, GPIIA

    基因ID

    5175

    途径

    Regulation of Actin Filament Polymerization
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