Cyclin A 抗体
Quick Overview for Cyclin A 抗体 (ABIN2740254)
抗原
See all Cyclin A (CCNA2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Bovine Cyclin A1+2
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纯化方法
- Protein G purified
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免疫原
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Full length bovine protein.
Type of Immunogen: Recombinant protein -
亚型
- IgG2a kappa
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应用备注
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (1 - 2 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody recognizes a protein of 54 kDa, which is identified as Cyclin A. Its epitope is located amino acids 144-148 of the human protein. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase. ELISA: Order BSA-free antibody format for coating. -
说明
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Target Species of Antibody: Bovine
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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别名
- Cyclin A
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途径
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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