TP53I3 抗体
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北京 101111
Quick Overview for TP53I3 抗体 (ABIN2734080)
抗原
See all TP53I3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.
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亚型
- IgG1
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应用备注
- WB 1:2000,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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别名
- TP53I3
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背景
- The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
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分子量
- 35.4 kDa
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基因ID
- 9540
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NCBI登录号
- NM_147184
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HGNC
- 9540
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途径
- p53 Pathway
抗原
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