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PSMA 抗体

FOLH1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 2E1 unconjugated
产品编号 ABIN2729879
发货至: 中国
  • 抗原 See all PSMA (FOLH1) 抗体
    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
    适用
    • 66
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 猴
    宿主
    • 38
    • 29
    • 1
    小鼠
    克隆类型
    • 37
    • 31
    单克隆
    标记
    • 44
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMA antibody is un-conjugated
    应用范围
    • 40
    • 29
    • 28
    • 16
    • 11
    • 11
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.
    克隆位点
    2E1
    亚型
    IgG2b
    Top Product
    Discover our top product FOLH1 Primary Antibody
  • 应用备注
    WB 1:500~2000, IF 1:100,
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
    别名
    FOLH1 (FOLH1 产品)
    别名
    FGCP antibody, FOLH antibody, GCP2 antibody, GCPII antibody, NAALAD1 antibody, NAALAdase antibody, PSM antibody, PSMA antibody, mGCP antibody, mopsm antibody, Naalad antibody, putative N-acetylated-alpha-linked acidic dipeptidase antibody, folate hydrolase 1B antibody, folate hydrolase 1 antibody, folate hydrolase (prostate-specific membrane antigen) 1 antibody, LOC451185 antibody, FOLH1B antibody, FOLH1 antibody, Folh1 antibody
    背景
    This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
    分子量
    84.2 kDa
    基因ID
    2346
    NCBI登录号
    NM_004476
    HGNC
    2346
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