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MYD88 抗体

MYD88 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 2B2 unconjugated
产品编号 ABIN2726635
发货至: 中国
  • 抗原 See all MYD88 抗体
    MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
    适用
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    宿主
    • 86
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    小鼠
    克隆类型
    • 79
    • 22
    单克隆
    标记
    • 61
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    This MYD88 antibody is un-conjugated
    应用范围
    • 82
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    产品特性
    Homo sapiens myeloid differentiation primary response gene (88) (MYD88), transcript variant 2
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
    克隆位点
    2B2
    亚型
    IgG2a
    Top Product
    Discover our top product MYD88 Primary Antibody
  • 应用备注
    WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Mendez, Banerjee: "Proximal Ligation Assay (PLA) on Lung Tissue and Cultured Macrophages to Demonstrate Protein-protein Interaction." in: Bio-protocol, Vol. 7, Issue 21, (2017) (PubMed).

    Caner, Sen Turk, Baris, Cetin, Tepeli, Hacioglu, Sari, Zencir, Dogu, Bagci, Keskin: "MYD88 Expression and L265P Mutation in Mature B-Cell Non-Hodgkin Lymphomas." in: Genetic testing and molecular biomarkers, Vol. 19, Issue 7, pp. 372-8, (2015) (PubMed).

    Choi, Kim, Lee, Kim: "MYD88 expression and L265P mutation in diffuse large B-cell lymphoma." in: Human pathology, (2013) (PubMed).

  • 抗原
    MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
    别名
    MYD88 (MYD88 产品)
    背景
    This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
    分子量
    33.1 kDa
    基因ID
    4615
    NCBI登录号
    NM_002468
    HGNC
    4615
    途径
    NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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