MYD88 抗体
(3 references)Quick Overview for MYD88 抗体 (ABIN2726635)
抗原
See all MYD88 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens myeloid differentiation primary response gene (88) (MYD88), transcript variant 2
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
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亚型
- IgG2a
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anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 201-296) antibody
MYD88 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 32-265) antibodyMYD88 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (Internal Region) antibodyVerified MYD88 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 44-264) antibodyMYD88 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 136-164) antibodyMYD88 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibodyMYD88 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibodyMYD88 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Proximal Ligation Assay (PLA) on Lung Tissue and Cultured Macrophages to Demonstrate Protein-protein Interaction." in: Bio-protocol, Vol. 7, Issue 21, (2017) (PubMed).
: "MYD88 Expression and L265P Mutation in Mature B-Cell Non-Hodgkin Lymphomas." in: Genetic testing and molecular biomarkers, Vol. 19, Issue 7, pp. 372-8, (2015) (PubMed).
: "MYD88 expression and L265P mutation in diffuse large B-cell lymphoma." in: Human pathology, (2013) (PubMed).
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: "Proximal Ligation Assay (PLA) on Lung Tissue and Cultured Macrophages to Demonstrate Protein-protein Interaction." in: Bio-protocol, Vol. 7, Issue 21, (2017) (PubMed).
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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别名
- MYD88
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背景
- This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
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分子量
- 33.1 kDa
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基因ID
- 4615
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NCBI登录号
- NM_002468
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HGNC
- 4615
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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