alpha 1 Adrenergic Receptor 抗体
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Quick Overview for alpha 1 Adrenergic Receptor 抗体 (ABIN272286)
抗原
See all alpha 1 Adrenergic Receptor (ADRA1A) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AR-alpha1A protein. (region surrounding Gln365)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Adrenoceptor alpha 1A (ADRA1A) (AA 346-475) antibody
ADRA1A 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (Internal Region) antibodyADRA1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) antibodyKD Validated ADRA1A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB4190 unconjugated Recombinant Antibody
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 206-270) antibodyADRA1A 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 335-373), (C-Term) antibodyADRA1A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 1-27) antibodyADRA1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G8 unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 6-22) antibodyADRA1A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 330-466) antibodyADRA1A 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 171-183), (C176S), (Extracellular) antibodyADRA1A 适用: 人 WB, IF, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (C-Term) antibodyADRA1A 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
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别名
- alpha-1A Adrenergic Receptor
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背景
- Alpha1A-adrenergic receptors (alpha1A-ARs) mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. alpha1A-AR couples to Gq/11 and regulates blood pressure due to changes in vascular tone and cardiac output. Alternative splicing of the ADRA1A gene generates four isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. alpha1A-AR transcripts are abundant in heart, brain, liver and prostate. alpha1A-AR transcript sizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. Transcripts of 6.0, 4.0 and 3.0 kb have been detected in heart, and transcripts of 6.0 and 4.0 kb have been detected in prostate.Synonyms: ADRA1A, ADRA1C, Alpha 1A-adrenoceptor, Alpha 1A-adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c
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分子量
- approx. 51 kDa
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基因ID
- 148
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NCBI登录号
- NP_000671
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UniProt
- P35348
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途径
- AMPK Signaling
抗原
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