alpha 1 Adrenergic Receptor 抗体 (2nd Extracellular Loop, C176S)
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Quick Overview for alpha 1 Adrenergic Receptor 抗体 (2nd Extracellular Loop, C176S) (ABIN7042908)
抗原
See all alpha 1 Adrenergic Receptor (ADRA1A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 2nd Extracellular Loop, AA 171-183, C176S
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原理
- A Rabbit Polyclonal Antibody to α1A-Adrenergic Receptor
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human,rat,mouse,bovine - 12,13 amino acid residues identical
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产品特性
- Anti-alpha1A-Adrenergic Receptor (extracellular) Antibody is directed against an extracellular epitope of the human α1A-adrenergic receptor. Anti-α1A-Adrenergic Receptor (extracellular) Antibody (ABIN7042908, ABIN7043908 and ABIN7043909) can be used in western blot and immunohistochemistry applications. It has been designed to recognize α1A-adrenoceptor from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- EDETI*SQINEEPG(C), corresponding to amino acid residues 171-183 of human alpha1A-adrenoceptor with replacement of cysteine 176 (C176) with serine (*S)
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亚型
- IgG
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anti-Adrenoceptor alpha 1A (ADRA1A) (AA 346-475) antibody
ADRA1A 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (Internal Region) antibodyADRA1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) antibodyKD Validated ADRA1A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB4190 unconjugated Recombinant Antibody
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 206-270) antibodyADRA1A 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 335-373), (C-Term) antibodyADRA1A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 1-27) antibodyADRA1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G8 unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 6-22) antibodyADRA1A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 330-466) antibodyADRA1A 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (C-Term) antibodyADRA1A 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7234685)
Blocking Peptide: (ABIN7234685)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
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别名
- ADRA1A
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背景
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Synonyms: Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, α1A-AR, ADRA1A
Description: Adrenergic receptors (also called adrenoceptors) are the receptors for the catecholamines adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions.Adrenergic receptors are members of the G-protein coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.Adrenoceptors are divided into three types: α1, α2 and β adrenoceptors. Each type is further divided into at least three subtypes: α1A, α1B, α1D, α2A, α2B, α2C, β1, β2, β3.1,2 They are expressed in nearly all peripheral tissues and in the central nervous system.1,2All α1-adrenoceptors (α1-ARs) activate phospholipases C and A2.3 In addition to mobilizing intracellular calcium, the α1-ARs have also been shown to activate calcium influx via voltage-dependent and -independent calcium channels.4The α1A-ARs have at least nine known alternative spliced isoforms. They are the most abundant adrenergic receptor in the brain, and are considered postsynaptic receptors. α1A-ARs are also expressed in the heart, liver and prostate.
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基因ID
- 148
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NCBI登录号
- NM_033303
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UniProt
- P35348
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途径
- AMPK Signaling
抗原
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