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Serotonin Receptor 1A 抗体

The 兔 多克隆 anti-Serotonin Receptor 1A antibody (ABIN272268) specifically detects Serotonin Receptor 1A in WB, IF 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN272268
发货至: 中国
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Quick Overview for Serotonin Receptor 1A 抗体 (ABIN272268)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

  • 49
  • 33
  • 32
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 44
  • 5
  • 2

克隆类型

  • 47
  • 4
多克隆

标记

  • 25
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Serotonin Receptor 1A antibody is un-conjugated

应用范围

  • 36
  • 18
  • 15
  • 13
  • 13
  • 10
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of SR-1A protein. (region surrounding Phe321)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 90 % pure SDS-PAGE
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Serotonin Receptor 1A (HTR1A)

    背景

    The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic bound to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the α2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories,designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A,-1B, -1D, -1E and -1F.Synonyms: 5-HT-1A, 5-HT1A, 5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1

    分子量

    approx. 46 kDa

    基因ID

    3350

    NCBI登录号

    NP_000515

    UniProt

    P08908

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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