TP53I3 抗体
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- 抗原 See all TP53I3 抗体
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TP53I3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of PIG3 protein. (region surrounding Leu265)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product TP53I3 Primary Antibody
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anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 163-332) antibody
TP53I3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (C-Term) antibodyTP53I3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
- 别名
- TP53I3 (TP53I3 产品)
- 别名
- MGC82892 antibody, MGC146409 antibody, PIG3 antibody, tumor protein p53 inducible protein 3 antibody, tumor protein p53 inducible protein 3 S homeolog antibody, Tp53I3 antibody, quinone oxidoreductase PIG3 antibody, TP53I3 antibody, tp53i3.S antibody, tp53i3 antibody, tp53I3 antibody
- 背景
- The PIG (p53-induced gene) gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. One member of the PIG gene family, p53-inducible gene 3 (PIG3), is a p53 responsive gene that maps, in humans, to chromosome 2p and encodes a protein with significant homology to oxidoreductases. Oxidoreductases are enzymes involved in cellular responses to oxidative stress and irradiation, and they influence the involvement of PIG3 in the metabolism of reactive oxygen species. PIG3 is localized to the cytoplasm and induced in primary, non-transformed, and transformed cell cultures after exposure to genotoxic agents. The induction of PIG3 is p53 dependent and occurs with delayed kinetics as compared with other p53 downstream targets. PIG3 may act with caspase-8 as a key regulatory element in p53-dependent transcriptional deregulation by triggering the caspase cascade and mitochondrial breakdown. PIG3 is highly up-regulated by p53 and may be useful for detecting transient activation of p53.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein
- 分子量
- approx. 36 kDa
- 基因ID
- 9540
- NCBI登录号
- NP_001193731
- UniProt
- Q53FA7
- 途径
- p53 Pathway
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