TOP3B 抗体
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- 抗原 See all TOP3B 抗体
- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TOP3B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Topo IIIbeta-1 protein. (region surrounding Gln84)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product TOP3B Primary Antibody
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anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-862) antibody
TOP3B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F11 unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-862) antibodyTOP3B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-250) antibodyTOP3B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (C-Term) antibodyTOP3B 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (N-Term) antibodyTOP3B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) antibodyTOP3B 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-862) antibodyTOP3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-270) antibodyTOP3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
- 别名
- TOP3B (TOP3B 产品)
- 别名
- TOP3B1 antibody, top3b antibody, DNA topoisomerase III beta antibody, topoisomerase (DNA) III beta antibody, DNA topoisomerase III beta L homeolog antibody, TOP3B antibody, Top3b antibody, top3b.L antibody
- 背景
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA by transiently breaking and rejoining DNA strands. Although DNA topoisomerase I and DNA topoisomerase II relax both positive and negative supercoils, DNA topoisomerase III relaxes only negative supercoils. DNA topoisomerase III alpha exists as a long and a short isoform, which are produced by alternative splicing. DNA topoisomerase III alpha, which localizes to the nucleolus, is constitutively expressed and remains at high levels throughout the cell cycle in HL-60 cells. DNA topoisomerase III beta exists as three isoforms, namely beta1, beta2 and beta3, also produced by alternative splicing. DNA topoisomerase III beta1 is expressed in testes, heart and skeletal muscle, whereas beta2 is expressed in thymus, kidney and pancreas.Synonyms: DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B1
- 分子量
- approx. 96 kDa
- 基因ID
- 8940
- NCBI登录号
- NP_003926
- UniProt
- O95985
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