WASF1 抗体
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Quick Overview for WASF1 抗体 (ABIN272093)
抗原
See all WASF1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of WAVE1 protein. (region surrounding Ile119)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-WAS Protein Family, Member 1 (WASF1) (AA 381-553) antibody
WASF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (Internal Region) antibodyWASF1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) antibodyWASF1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4605 unconjugated Recombinant Antibody
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (AA 91-140) antibodyWASF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (Tyr410) antibodyWASF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (AA 91-140), (pTyr125) antibodyWASF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 1000approx. 1: 5000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- WASF1 (WAS Protein Family, Member 1 (WASF1))
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别名
- WASF1 / WAVE1
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背景
- WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases. The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac. The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments. WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes.Synonyms: KIAA0269, SCAR1, Verprolin homology domain-containing protein 1, WASP family protein member 1, WAVE-1, Wiskott-Aldrich syndrome protein family member 1
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分子量
- approx. 65 kDa
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基因ID
- 8936
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NCBI登录号
- NP_001020105
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UniProt
- Q92558
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途径
- RTK signaling, Regulation of Actin Filament Polymerization
抗原
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