MSK1 抗体
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- 抗原 See all MSK1 (RPS6KA5) 抗体
- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MSK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of MSK1 protein. (region surrounding Met355)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product RPS6KA5 Primary Antibody
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anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 224-367) antibody
RPS6KA5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 271-370) antibodyRPS6KA5 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer376) antibodyRPS6KA5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 540-665) antibodyRPS6KA5 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 1-802) antibodyRPS6KA5 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) antibodyRPS6KA5 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (Ser212) antibodyRPS6KA5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (Internal Region) antibodyRPS6KA5 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer360) antibodyRPS6KA5 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer212) antibodyRPS6KA5 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1000approx. 1/5000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
- 别名
- RPS6KA5 / MSK1 (RPS6KA5 产品)
- 别名
- MSK1 antibody, MSPK1 antibody, RLPK antibody, 3110005L17Rik antibody, 6330404E13Rik antibody, AI854034 antibody, Msk1 antibody, ribosomal protein S6 kinase A5 antibody, ribosomal protein S6 kinase, polypeptide 5 antibody, RPS6KA5 antibody, Rps6ka5 antibody
- 背景
- MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK-1can be activated by ERK1/2 and SAPK2 /p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress. Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal kinase domain of MSK-1 which is essential for the catalytic activity of the N-terminal kinase domain.Synonyms: 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, Ribosomal protein S6 kinase alpha-5
- 分子量
- approx. 90 kDa
- 基因ID
- 9252
- NCBI登录号
- NP_004746
- UniProt
- O75582
- 途径
- MAPK Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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