MSK1 抗体 (AA 540-665)
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- 抗原 See all MSK1 (RPS6KA5) 抗体
- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
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抗原表位
- AA 540-665
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MSK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Ribosomal protein S6 kinase alpha-5(RPS6KA5) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Ribosomal protein S6 kinase alpha-5(RPS6KA5) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: ribosomal protein S6 kinase, 90 kDa, polypeptide 5
Protein Name: Ribosomal protein S6 kinase alpha-5 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MSK1 recombinant protein (Position: V540-Q665). Human MSK1 shares 98% amino acid (aa) sequence identity with mouse MSK1.
- 亚型
- IgG
- Top Product
- Discover our top product RPS6KA5 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for MSK1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
- 别名
- RPS6KA5 (RPS6KA5 产品)
- 别名
- MSK1 antibody, MSPK1 antibody, RLPK antibody, 3110005L17Rik antibody, 6330404E13Rik antibody, AI854034 antibody, Msk1 antibody, ribosomal protein S6 kinase A5 antibody, ribosomal protein S6 kinase, polypeptide 5 antibody, RPS6KA5 antibody, Rps6ka5 antibody
- 背景
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Ribosomal protein S6 kinase alpha-5, also known as MSK1, is an enzyme that in humans is encoded by the RPS6KA5 gene. It belongs to the AGC family of kinases. MSK1 gene is mapped to chromosome 14q31-q32. Northern blot analysis indicated that MSK1 was expressed as a 4-kb mRNA in all tissues tested, with the highest levels of expression in brain, muscle, and placenta. MSK1 was activated in vitro and in vivo by either ERK or SAPK2 proteins. It has been found that MSK1, rather than MAPKAP-K1 or MAPKAP-K2/K3, mediates activation of the cAMP response element-binding protein and activating transcription factor-1 by either growth factors or stress signals.
Synonyms: 90 kDa ribosomal protein S6 kinase 5 antibody|KS6A5_HUMAN antibody|MGC1911 antibody|Mitogen and stress activated protein kinase 1 antibody|MSPK1 antibody|Nuclear Mitogen And Stress Activated Protein Kinase 1 antibody|Nuclear mitogen- and stress-activated protein kinase 1 antibody|Ribosomal protein S6 kinase 90kD polypeptide 5 antibody|Ribosomal protein S6 kinase 90 kDa antibody|Ribosomal protein S6 kinase 90 kDa polypeptide 5 antibody|Ribosomal Protein S6 Kinase Alpha 5 antibody|Ribosomal protein S6 kinase alpha-5 antibody|RLPK antibody|RPS6KA5 antibody|RSK Like Protein Kinase antibody|RSK-like protein kinase antibody|RSKL antibody|S6K alpha 5 antibody|S6K-alpha-5 antibody - 基因ID
- 9252
- UniProt
- O75582
- 途径
- MAPK Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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