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TGFB3 抗体

TGFB3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN271851
发货至: 中国
  • 抗原 See all TGFB3 抗体
    TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
    适用
    • 42
    • 21
    • 20
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 3
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 28
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGFB3 antibody is un-conjugated
    应用范围
    • 30
    • 20
    • 15
    • 8
    • 7
    • 6
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of pro-TGF-beta-3 (47 kDa) and cleaved-TGF-beta-3 (13 kDa) protein. (region surrounding Gly292)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product TGFB3 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
    别名
    TGF-beta-3 (TGFB3) (TGFB3 产品)
    别名
    TGFB3 antibody, ARVD antibody, TGF-beta3 antibody, Tgfb-3 antibody, TGF-B3 antibody, TGFbeta3 antibody, wu:fc78g09 antibody, zgc:92058 antibody, transforming growth factor beta 3 antibody, transforming growth factor, beta 3 antibody, TGFB3 antibody, Tgfb3 antibody, tgfb3 antibody
    背景
    Transforming Growth Factor beta 3 (TGF beta 3) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional, capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors, and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. A high level of TGF beta 3 in normal adult heart, lung, and brain suggests a possible role for this factor in the regulation of a variety of normal physiological functions. The expression of TGF beta 3 in different locations and at specific stages of embryogenesis suggests its involvement in the regulation of development. Similar to the other isoforms of TGF beta, the upregulated activation of TGF beta 3 might also be involved in a variety of pathological conditions. TGF beta 3 has been detected in human, porcine, and avian sources and is expressed in cells of mesenchymal origin, suggesting a different role for this protein than for TGF beta 1 or TGF beta 2. TGF beta 3 is less prevalent in natural expression than either TGF beta 1 or TGF beta 2, but is the most abundant mRNA expressed in chick embryos. It is also expressed in human umbilical cord and in several human carcinoma cells.Synonyms: Transforming growth factor beta-3
    分子量
    13 and 47 kDa
    基因ID
    7043
    NCBI登录号
    NP_003230
    UniProt
    P10600
    途径
    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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