TGFB3 抗体
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Quick Overview for TGFB3 抗体 (ABIN271851)
抗原
See all TGFB3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of pro-TGF-beta-3 (47 kDa) and cleaved-TGF-beta-3 (13 kDa) protein. (region surrounding Gly292)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibody
TGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) antibodyTGFB3 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 298-409) antibodyTGFB3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (C-Term) antibodyTGFB3 适用: 人, 大鼠, 小鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 274-372) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) antibodyTGFB3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 25-300) antibodyTGFB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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别名
- TGF-beta-3 (TGFB3)
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背景
- Transforming Growth Factor beta 3 (TGF beta 3) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional, capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors, and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. A high level of TGF beta 3 in normal adult heart, lung, and brain suggests a possible role for this factor in the regulation of a variety of normal physiological functions. The expression of TGF beta 3 in different locations and at specific stages of embryogenesis suggests its involvement in the regulation of development. Similar to the other isoforms of TGF beta, the upregulated activation of TGF beta 3 might also be involved in a variety of pathological conditions. TGF beta 3 has been detected in human, porcine, and avian sources and is expressed in cells of mesenchymal origin, suggesting a different role for this protein than for TGF beta 1 or TGF beta 2. TGF beta 3 is less prevalent in natural expression than either TGF beta 1 or TGF beta 2, but is the most abundant mRNA expressed in chick embryos. It is also expressed in human umbilical cord and in several human carcinoma cells.Synonyms: Transforming growth factor beta-3
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分子量
- 13 and 47 kDa
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基因ID
- 7043
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NCBI登录号
- NP_003230
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UniProt
- P10600
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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