CDK2 抗体
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- 抗原 See all CDK2 抗体
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CDK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- 产品特性
- Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human CDK2 (NP_001789) produced in HEK293T cell.
- 克隆位点
- 6H2
- 亚型
- IgG2b
- Top Product
- Discover our top product CDK2 Primary Antibody
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- 应用备注
- WB 1:2000, IF 1:100, FLOW 1:100
- 说明
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The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- 别名
- CDK2 (CDK2 产品)
- 背景
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.
- 分子量
- 33.7 kDa
- 基因ID
- 1017
- NCBI登录号
- NM_001798
- HGNC
- 1017
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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