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CDK2 抗体

This anti-CDK2 antibody is a 小鼠 单克隆 antibody detecting CDK2 in WB, FACS 和 IF. Suitable for 人.
产品编号 ABIN2718390
发货至: 中国

Quick Overview for CDK2 抗体 (ABIN2718390)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

6H2
  • 产品特性

    Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human CDK2 (NP_001789) produced in HEK293T cell.

    亚型

    IgG2b
  • 应用备注

    WB 1:2000, IF 1:100, FLOW 1:100

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    CDK2

    背景

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

    分子量

    33.7 kDa

    基因ID

    1017

    NCBI登录号

    NM_001798

    HGNC

    1017

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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