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Interleukin 17a 抗体 (Biotin)

IL17A 适用: 小鼠 ELISA, WB 宿主: 大鼠 Monoclonal TC11 Biotin
产品编号 ABIN2689740
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
    • 90
    • 42
    • 19
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    小鼠
    宿主
    • 62
    • 40
    • 17
    • 7
    • 3
    大鼠
    克隆类型
    • 71
    • 57
    • 1
    单克隆
    标记
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    This Interleukin 17a antibody is conjugated to Biotin
    应用范围
    • 71
    • 61
    • 31
    • 14
    • 11
    • 11
    • 10
    • 10
    • 9
    • 8
    • 6
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    ELISA, Western Blotting (WB)
    品牌
    BD Pharmingen™
    产品特性
    The TC11-8H4 monoclonal antibody specifically binds to recombinant and natural mouse IL-17A proteins. IL-17A, also known as Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8), is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro, it can also stimulate granulopoiesis in vivo. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8- thymocytes. Standard Curve Mouse IL-17A

    BD Pharmingen™ Biotin Rat Anti-Mouse IL-17A - Biotin - Clone TC11-8H4 - Isotype Rat IgG1, κ - Reactivity Ms - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Recombinant mouse IL-17A
    克隆位点
    TC11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Dong: "Mouse Th17 cells: current understanding of their generation and regulation." in: European journal of immunology, Vol. 39, Issue 3, pp. 640-4, (2009) (PubMed).

    Coquet, Chakravarti, Kyparissoudis, McNab, Pitt, McKenzie, Berzins, Smyth, Godfrey: "Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 32, pp. 11287-92, (2008) (PubMed).

    Lampropoulou, Hoehlig, Roch, Neves, Calderón Gómez, Sweenie, Hao, Freitas, Steinhoff, Anderton, Fillatreau: "TLR-activated B cells suppress T cell-mediated autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4763-73, (2008) (PubMed).

    Schwarzenberger, La Russa, Miller, Ye, Huang, Zieske, Nelson, Bagby, Stoltz, Mynatt, Spriggs, Kolls: "IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 11, pp. 6383-9, (1998) (PubMed).

  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL-17A (IL17A 产品)
    别名
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    背景
    Synonyms: IL-17, Il17, IL-17A, Il17a, CTLA-8, Ctla8, Interleukin-17A, interleukin 17A
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