IL12 抗体 (Biotin)
Quick Overview for IL12 抗体 (Biotin) (ABIN2689728)
抗原
See all IL12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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The C17.8 antibody reacts with the free p40 monomer of IL-12 as well as the p40 subunit complexed as homodimer or complexed with p35 as a p70 heterodimer.
BD Pharmingen™ Biotin Rat Anti-Mouse IL-12 (p40/p70) - Biotin - Clone C17.8 - Isotype Rat IgG2a - Reactivity Ms - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Recombinant Mouse IL-12 p70
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Antibodies to interleukin 12 abrogate established experimental colitis in mice." in: The Journal of experimental medicine, Vol. 182, Issue 5, pp. 1281-90, (1995) (PubMed).
: "Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice." in: European journal of immunology, Vol. 25, Issue 3, pp. 672-6, (1995) (PubMed).
: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).
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: "Antibodies to interleukin 12 abrogate established experimental colitis in mice." in: The Journal of experimental medicine, Vol. 182, Issue 5, pp. 1281-90, (1995) (PubMed).
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- IL12 (Interleukin 12 (IL12))
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别名
- IL-12 p40,p70
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途径
- JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
抗原
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