CD59 抗体
(3 references)Quick Overview for CD59 抗体 (ABIN2689346)
抗原
See all CD59 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Reacts with CD59, a 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein, expressed on hematopoietic and non-hematopoietic cells. Because of its role in interaction with complement activated products, CD59 has been termed membrane-attack-complex-inhibitory factor (MACIF), homologus restriction factor (HRF20), membrane inhibitor of reactive lysis (MIRL) and protectin. It inhibits the cytolytic activity of complement by binding to C8 and C9, thereby blocking the assembly of the membrane attack complex. CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2 and plays a role in T-cell activation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of glycosylphosphatidylinositol (GPI) anchor-defective mutant cell line analyzed on a FACScan Profile of K562 cells expressing glycosylphosphatidylinositol (GPI) anchor protein analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD59 - Purified - Clone p282 (H19) - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG2a kappa
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anti-CD59 (CD59) (AA 31-111) antibody
CD59 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8D2B8 unconjugated
anti-CD59 (CD59) (AA 74-110) antibodyCD59 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB56691 unconjugated
anti-CD59 (CD59) antibodyCD59 适用: 人, 小鼠 WB, FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-43-5 unconjugated
anti-CD59 (CD59) antibodyCD59 适用: 人 FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-43 unconjugated
anti-CD59 (CD59) (AA 31-111) antibodyCD59 适用: 人 WB, FACS, IHC, ELISA, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CD59 (CD59) (AA 23-105) antibodyCD59 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD59 (CD59) (AA 1-128) antibodyCD59 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-CD59 (CD59) (AA 52-100) antibodyCD59 适用: 人 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD59 (CD59) (AA 26-102) antibodyCD59 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD59 (CD59) antibodyCD59 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2E11B6 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Membrane defence against complement lysis: the structure and biological properties of CD59." in: Immunologic research, Vol. 12, Issue 3, pp. 258-75, (1994) (PubMed).
: "CD58 and CD59 molecules exhibit potentializing effects in T cell adhesion and activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 3, pp. 672-7, (1992) (PubMed).
: "CD59 molecule: a second ligand for CD2 in T cell adhesion." in: European journal of immunology, Vol. 22, Issue 11, pp. 2943-7, (1992) (PubMed).
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: "Membrane defence against complement lysis: the structure and biological properties of CD59." in: Immunologic research, Vol. 12, Issue 3, pp. 258-75, (1994) (PubMed).
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- CD59
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别名
- CD59
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途径
- Complement System
抗原
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