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CCR5 抗体 (AA 9-30)

Name: CCR5 抗体 (AA 9-30)
SKU: ABIN2689055
Availability: OutOfStock

This anti-CCR5 antibody is a 大鼠单克隆 antibody detecting CCR5 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.

(2 references)

产品编号 ABIN2689055

发货至: 中国

Quick Overview for CCR5 抗体 (AA 9-30) (ABIN2689055)

抗原

See all CCR5 抗体

CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

小鼠

宿主

大鼠

克隆类型

单克隆

标记

This CCR5 antibody is un-conjugated

应用范围

Flow Cytometry (FACS)

克隆位点

C34

Discover our top product CCR5 Primary Antibody

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AA 9-30

品牌

BD Pharmingen™

产品特性

The C34-3448 antibody reacts with mouse chemokine receptor CD195 (also known as CCR5), a member of the β- chemokine receptor family. CD195 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation. It signals a response to at least three chemokines: RANTES and macrophage inflammatory protein-1 (MIP-1)α and β. In the mouse system, the gene for CD195 has been mapped to chromosome 9. CD195 mRNA is expressed in heart, spleen and liver tissues, and by macrophages and T-lymphocytes. The immunogen used to generate the C34- 3448 hybridoma was a KLH-conjugated peptide consisting of amino acids 9-30 of mouse CD195 (CCR5). Expression of mouse CD195 by stimulated mouse splenocytes. BALB/c splenocytes were stimulated for 24 hours with ConA (10 μg/mL, final concentration, Sigma). The splenocytes were cultured for additional 5 days in the presence of mouse IL-2 (100 U/mL, final concentration, Cat. No. 550069). The splenocytes were stained with purified rat anti-mouse CD195 antibody (C34- 3448), followed by biotinylated mouse anti-rat IgG2c (A92-1, Cat. No. 553909) and Streptavidin- hycoerythrin (Cat. No. 554061) following BD Pharmingen's staining protocol (see Figure, Left panel). The data reflects gating on lymphocytes, based on forward and side scattered light signals. The level of nonspecific staining was assessed using the purified rat IgG2c isotype control (purified A23-1, Cat. No. 553982, Right panel). The quadrant markers for the bivariate dot plots were set based on the autofluorescence control and isotype control.

BD Pharmingen™ Purified Rat Anti-Mouse CD195 - Purified - Clone C34-3448 - Isotype Rat IgG2c, κ - Reactivity Ms - 0.5 mg

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Mouse CCR5 aa. 9-30

亚型

IgG2c kappa
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人 IHC (fro) 宿主: 小鼠 Monoclonal 12D1 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人, 大鼠 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6G11D1 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 19-34), (N-Term) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 201-300) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 151-200) antibody
CCR5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibody
CCR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibody
CCR5 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-22) antibody
CCR5 适用: 人 WB, ELISA, FACS, IP, ICC 宿主: 小鼠 Monoclonal T21-8 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (pSer336) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 100-200) antibody
CCR5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Aqueous buffered solution containing ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store undiluted at 4°C.
Meyer, Coyle, Proudfoot, Wells, Power: "Cloning and characterization of a novel murine macrophage inflammatory protein-1 alpha receptor." in: The Journal of biological chemistry, Vol. 271, Issue 24, pp. 14445-51, (1996) (PubMed).

Napolitano, Seamon, Leonard: "Identification of cell surface receptors for the Act-2 cytokine." in: The Journal of experimental medicine, Vol. 172, Issue 1, pp. 285-9, (1990) (PubMed).
抗原

CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

别名

CD195

背景

Synonyms: CCR5

途径

Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size