LAMP2 抗体
(4 references)-
- 抗原 See all LAMP2 抗体
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This LAMP2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
- 品牌
- BD Pharmingen™
- 产品特性
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The M3/84 monoclonal antibody specifically binds to CD107b which is also known as Mac-3, Lysosome-associated membrane protein 2 (LAMP-2/Lamp2/Lamp II), and Lysosomal membrane glycoprotein type B (LGP-B). CD107b is a single-pass type I transmembrane glycoprotein that constitutes a major integral membrane protein of lysosomes and may play a role in lysosomal function. CD107b is also expressed on the surface of mouse mononuclear phagocytes. Surface expression of the 92-110- kDa glycoprotein antigen increases during differentiation of monocytes to activated macrophages and may play a role in adhesion. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue. Immunohistochemical staining of macrophages. The formalin-fixed paraffin-embedded sections of normal mouse lung were stained with M3/84 mAb (left panel) or R3-34 mAb (isotype control, right panel). Macrophages are identified by the brown labeling of their cell -surface membranes.
BD Pharmingen™ Purified Rat Anti-Mouse CD107b - Purified - Clone M3/84 - Isotype Rat IgG1, κ - Reactivity Ms - 1 mL - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse C57Bl/6 peritoneal exudate cells
- 克隆位点
- M3-84
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product LAMP2 Primary Antibody
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anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 191-362) antibody
LAMP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-168) antibodyLAMP2 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6A10H10 unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-168) antibodyLAMP2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 8E2F2 unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 301-411) antibodyLAMP2 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 193-375) antibodyLAMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibodyLAMP2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibodyLAMP2 适用: 人 WB, FACS, ICC, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal H4B4 unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibodyKO Validated LAMP2 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 54-268) antibodyLAMP2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 30-127) antibodyLAMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G10 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 31.25 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Characterization of subsets of bone marrow-derived macrophages by flow cytometry analysis." in: Journal of leukocyte biology, Vol. 37, Issue 2, pp. 121-36, (1985) (PubMed).
: "Identification of two lysosomal membrane glycoproteins." in: The Journal of cell biology, Vol. 101, Issue 1, pp. 85-95, (1985) (PubMed).
: "Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets." in: The American journal of pathology, Vol. 111, Issue 1, pp. 112-24, (1983) (PubMed).
: "Expression and induction in vitro of macrophage differentiation antigens on murine cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 130, Issue 1, pp. 108-14, (1983) (PubMed).
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: "Characterization of subsets of bone marrow-derived macrophages by flow cytometry analysis." in: Journal of leukocyte biology, Vol. 37, Issue 2, pp. 121-36, (1985) (PubMed).
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