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ICAM2 抗体

ICAM2 适用: 小鼠 FACS, IP, IHC (fro), IHC (p), BR 宿主: 大鼠 Monoclonal 3C4 unconjugated
产品编号 ABIN2688871
发货至: 中国
  • 抗原 See all ICAM2 抗体
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    适用
    • 62
    • 25
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    小鼠
    宿主
    • 52
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    大鼠
    克隆类型
    • 52
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    单克隆
    标记
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    This ICAM2 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Blocking Reagent (BR)
    品牌
    BD Pharmingen™
    产品特性
    The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Rat Anti-Mouse CD102 - Purified - Clone 3C4(mIC2/4) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Transfected Cell Line
    克隆位点
    3C4
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ICAM2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos: "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness." in: Immunity, Vol. 10, Issue 1, pp. 9-19, (1999) (PubMed).

    Xu, Bickford, Luther, Carpenito, Takei, Springer: "Characterization of murine intercellular adhesion molecule-2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 12, pp. 4909-14, (1996) (PubMed).

    Xu, Tong, De Fougerolles, Springer: "Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 8, pp. 2650-5, (1992) (PubMed).

  • 抗原
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    别名
    CD102 (ICAM2 产品)
    别名
    ICAM2 antibody, CD102 antibody, Icam-2 antibody, Ly-60 antibody, intercellular adhesion molecule 2 antibody, LOC506088 antibody, ICAM2 antibody, LOC616254 antibody, LOC100140873 antibody, Icam2 antibody
    背景
    Synonyms: ICAM-2
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