EZH2 抗体 (AA 1-370)
Quick Overview for EZH2 抗体 (AA 1-370) (ABIN2668958)
抗原
See all EZH2 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 1-370
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                                            纯化方法
- None
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                                            免疫原
- This EZH2 antibody was raised against a recombinant fusion protein corresponding to amino acids 1-370 of mouse EZH2.
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
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                        Avoid repeated freeze/thaw cycles and keep on ice when not in storage. 
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                                            储存条件
- -20 °C
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                                            储存方法
- Antibodies in solution can be stored at -20 °C for 2 years.
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                                            有效期
- 6 months
 
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                                            : "Loss of BAP1 function leads to EZH2-dependent transformation. ..."    in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015)         (PubMed).        
 : "Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ..." in: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 842-54, (2014) (PubMed).
 : "Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations. ..." in: The Journal of clinical investigation, Vol. 123, Issue 11, pp. 4627-40, (2014) (PubMed).
 : "Retinoic acid controls body axis extension by directly repressing Fgf8 transcription." in: Development (Cambridge, England), Vol. 141, Issue 15, pp. 2972-7, (2014) (PubMed).
 : "Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5012-22, (2014) (PubMed).
 : "Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. ..." in: Cancer cell, Vol. 24, Issue 5, pp. 660-72, (2013) (PubMed).
 : "A transcriptional repressor co-regulatory network governing androgen response in prostate cancers." in: The EMBO journal, Vol. 31, Issue 12, pp. 2810-23, (2012) (PubMed).
 : "ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression." in: Cancer cell, Vol. 22, Issue 2, pp. 180-93, (2012) (PubMed).
 : "Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 5, pp. 993-1006, (2010) (PubMed).
 
 
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                                            : "Loss of BAP1 function leads to EZH2-dependent transformation. ..."    in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015)         (PubMed).        
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    - EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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                                            别名
- EZH2
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                                            分子量
- 96 kDa
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                                            基因ID
- 2146
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                                            途径
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
 抗原
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