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EZH2 抗体 (AA 1-370)

Name: EZH2 抗体 (AA 1-370)
SKU: ABIN2668958
Availability: OutOfStock

Cited in 9+ publications. The 兔多克隆 anti-EZH2 antibody (ABIN2668958) specifically detects EZH2 in IP, ChIP 和 ChIP-seq. The antibody is reactive with 人和小鼠 samples.

ChIP

ChIP-seq

2 images

(9 references)

产品编号 ABIN2668958

发货至: 中国

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Quick Overview for EZH2 抗体 (AA 1-370) (ABIN2668958)

抗原

See all EZH2 抗体

EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This EZH2 antibody is un-conjugated

应用范围

Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Discover our top product EZH2 Primary Antibody

抗原表位
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1
AA 1-370

纯化方法

None

免疫原

This EZH2 antibody was raised against a recombinant fusion protein corresponding to amino acids 1-370 of mouse EZH2.
anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 51-285) antibody
EZH2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-194) antibody
EZH2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6G4F4 unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-296), (N-Term) antibody
EZH2 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23144 unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) antibody
EZH2 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 144CT2-1-1-5 unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 410-440) antibody
EZH2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2921 unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) antibody
EZH2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) antibody
KD Validated EZH2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7200 unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) antibody
EZH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-250) antibody
EZH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Enhancer of Zeste Homolog 2 (EZH2) antibody
KD Validated EZH2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB835 unconjugated Recombinant Antibody

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

储存条件

-20 °C

储存方法

Antibodies in solution can be stored at -20 °C for 2 years.

有效期

6 months
LaFave, Béguelin, Koche, Teater, Spitzer, Chramiec, Papalexi, Keller, Hricik, Konstantinoff, Micol, Durham, Knutson, Campbell, Blum, Shi, Doud, Krivtsov, Chung, Khodos, de Stanchina, Ouerfelli et al.: "Loss of BAP1 function leads to EZH2-dependent transformation. ..." in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015) (PubMed).

Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: "Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ..." in: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 842-54, (2014) (PubMed).

Inoue, Kitaura, Togami, Nishimura, Enomoto, Uchida, Kagiyama, Kawabata, Nakahara, Izawa, Oki, Maehara, Isobe, Tsuchiya, Harada, Harada, Ochiya, Aburatani, Kimura, Thol, Heuser, Levine, Abdel-Wahab et al.: "Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations. ..." in: The Journal of clinical investigation, Vol. 123, Issue 11, pp. 4627-40, (2014) (PubMed).

Kumar, Duester: "Retinoic acid controls body axis extension by directly repressing Fgf8 transcription." in: Development (Cambridge, England), Vol. 141, Issue 15, pp. 2972-7, (2014) (PubMed).

Tong, He, Xie, Mochizuki, Liu, Mochizuki, Meng, Sun, Zhang, Guo, Hexner, Zhang: "Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5012-22, (2014) (PubMed).

Bender, Tang, Lindroth, Hovestadt, Jones, Kool, Zapatka, Northcott, Sturm, Wang, Radlwimmer, Højfeldt, Truffaux, Castel, Schubert, Ryzhova, Seker-Cin, Gronych, Johann, Stark, Meyer, Milde, Schuhmann et al.: "Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. ..." in: Cancer cell, Vol. 24, Issue 5, pp. 660-72, (2013) (PubMed).

Chng, Chang, Tan, Yang, Hong, Sng, Cheung: "A transcriptional repressor co-regulatory network governing androgen response in prostate cancers." in: The EMBO journal, Vol. 31, Issue 12, pp. 2810-23, (2012) (PubMed).

Abdel-Wahab, Adli, LaFave, Gao, Hricik, Shih, Pandey, Patel, Chung, Koche, Perna, Zhao, Taylor, Park, Carroll, Melnick, Nimer, Jaffe, Aifantis, Bernstein, Levine: "ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression." in: Cancer cell, Vol. 22, Issue 2, pp. 180-93, (2012) (PubMed).

Bredfeldt, Greathouse, Safe, Hung, Bedford, Walker: "Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 5, pp. 993-1006, (2010) (PubMed).
抗原

EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

别名

EZH2

分子量

96 kDa

基因ID

2146

途径

Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation