电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Histone 3 抗体 (H3K18ac)

This 兔 多克隆 antibody specifically detects Histone 3 in WB, IF, ChIP, ICC, DB 和 ChIP-seq. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN2668428
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Histone 3 抗体 (H3K18ac) (ABIN2668428)

抗原

See all Histone 3 (H3) 抗体
Histone 3 (H3) (Histone H3 (H3))

适用

  • 1796
  • 1168
  • 1020
  • 48
  • 40
  • 37
  • 36
  • 32
  • 31
  • 23
  • 23
  • 19
  • 9
  • 8
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 1537
  • 290
  • 9
  • 5
  • 1

克隆类型

  • 1143
  • 698
  • 1
多克隆

标记

  • 976
  • 103
  • 67
  • 67
  • 67
  • 67
  • 67
  • 67
  • 42
  • 29
  • 28
  • 24
  • 24
  • 18
  • 18
  • 18
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 16
  • 7
  • 1
This Histone 3 antibody is un-conjugated

应用范围

  • 1449
  • 621
  • 519
  • 424
  • 370
  • 355
  • 251
  • 205
  • 204
  • 188
  • 177
  • 157
  • 121
  • 49
  • 48
  • 42
  • 37
  • 26
  • 25
  • 19
  • 19
  • 7
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Dot Blot (DB), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

    • 68
    • 59
    • 54
    • 54
    • 53
    • 51
    • 50
    • 49
    • 45
    • 40
    • 39
    • 39
    • 38
    • 36
    • 32
    • 32
    • 32
    • 31
    • 31
    • 30
    • 29
    • 27
    • 27
    • 26
    • 24
    • 23
    • 22
    • 22
    • 21
    • 20
    • 20
    • 19
    • 18
    • 17
    • 16
    • 15
    • 14
    • 14
    • 14
    • 13
    • 13
    • 12
    • 11
    • 11
    • 11
    • 11
    • 10
    • 10
    • 10
    • 10
    H3K18ac

    原理

    Histone H3K18ac antibody (pAb)

    纯化方法

    Protein A Chromatography

    免疫原

    This Histone H3 acetyl Lys18 antibody was raised against a peptide including acetyl-lysine 18 of histone H3.

    亚型

    IgG
  • 应用备注

    ChIP: 10 μg per ChIP ChIP-Seq: 4 μg each ICC/IF: 1 μg/mL dilution WB: 0.5 - 2 μg/mL dilution DB: 0.1 - 0.5 μg/mL dilution

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in PBS ( pH 7.5) with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Zhang, Li, Rezaeian, Xu, Chou, Jin, Han, Pan, Wang, Long, Zhang, Huang, Tsai, Tsai, Logothetis, Lin: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." in: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).

    Yasuma, Yasunaga, Takemoto, Sugata, Mitobe, Takenouchi, Nakagawa, Suzuki, Matsuoka: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." in: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).

    Cohen, Friedmann, Hwang, Marmorstein, Lee: "The microtubule-associated tau protein has intrinsic acetyltransferase activity." in: Nature structural & molecular biology, Vol. 20, Issue 6, pp. 756-62, (2013) (PubMed).

  • 抗原

    Histone 3 (H3) (Histone H3 (H3))

    别名

    Histone H3

    背景

    Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, these modifications play a major role in regulating gene expression. Acetylation of histones is linked to a number of specific processes including transcriptional regulation and genomic organization.

    分子量

    17 kDa

    基因ID

    3020

    NCBI登录号

    NP_003522
You are here: