SIRT1 抗体 (AA 581-630)
Quick Overview for SIRT1 抗体 (AA 581-630) (ABIN2668278)
抗原
See all SIRT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 581-630
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纯化方法
- Protein G Chromatography
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免疫原
- This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- 10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30 % glycerol, 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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储存条件
- -20 °C
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储存方法
- Antibodies in solution can be stored at -20 °C for 2 years.
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有效期
- 6 months
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HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates." in: Epigenetics, Vol. 8, Issue 6, pp. 612-23, (2013) (PubMed).
: "Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin." in: Molecular cell, Vol. 16, Issue 1, pp. 93-105, (2004) (PubMed).
: "
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HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates." in: Epigenetics, Vol. 8, Issue 6, pp. 612-23, (2013) (PubMed).
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- SIRT1 (Sirtuin 1 (SIRT1))
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别名
- SIRT1
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分子量
- 120 kDa
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基因ID
- 23411
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途径
- MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
抗原
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