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SIRT1 抗体 (AA 581-630)

This anti-SIRT1 antibody is a 小鼠 单克隆 antibody detecting SIRT1 in WB, IP, IF 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2668278
发货至: 中国

Quick Overview for SIRT1 抗体 (AA 581-630) (ABIN2668278)

抗原

See all SIRT1 抗体
SIRT1 (Sirtuin 1 (SIRT1))

适用

  • 159
  • 92
  • 64
  • 34
  • 5
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 149
  • 23
  • 2
  • 2
  • 1
小鼠

克隆类型

  • 130
  • 47
单克隆

标记

  • 84
  • 15
  • 11
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 3
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  • 1
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This SIRT1 antibody is un-conjugated

应用范围

  • 137
  • 54
  • 53
  • 50
  • 41
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  • 34
  • 29
  • 29
  • 17
  • 9
  • 4
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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

2G1-F7
  • 抗原表位

    • 32
    • 16
    • 16
    • 12
    • 9
    • 7
    • 6
    • 6
    • 5
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    • 3
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 581-630

    纯化方法

    Protein G Chromatography

    免疫原

    This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30 % glycerol, 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -20 °C

    储存方法

    Antibodies in solution can be stored at -20 °C for 2 years.

    有效期

    6 months
  • Rajendran, Kidane, Yu, Dashwood, Bisson, Löhr, Ho, Williams, Dashwood: "HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates." in: Epigenetics, Vol. 8, Issue 6, pp. 612-23, (2013) (PubMed).

    Vaquero, Scher, Lee, Erdjument-Bromage, Tempst, Reinberg: "Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin." in: Molecular cell, Vol. 16, Issue 1, pp. 93-105, (2004) (PubMed).

  • 抗原

    SIRT1 (Sirtuin 1 (SIRT1))

    别名

    SIRT1

    分子量

    120 kDa

    基因ID

    23411

    途径

    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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