TCF7 抗体
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北京 101111
Quick Overview for TCF7 抗体 (ABIN2666283)
抗原
See all TCF7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity purified
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亚型
- IgG1 kappa
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anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibody
TCF7 适用: 人 WB, IHC, IP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 287-384) antibodyTCF7 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 287-384) antibodyTCF7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 228-277) antibodyTCF7 适用: 人, Cow, 豚鼠, 马, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (Middle Region) antibodyTCF7 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibodyTCF7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Upon receipt, store undiluted between 2°C and 8°C.
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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别名
- TCF1
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背景
- TCF1 is the first identified member of the T-cell-specific transcription factor family. It plays an important role in T cell development and differentiation. TCF1 is inactivated by association with the transcriptional repressor TLE proteins. During Wnt signaling, the transcriptional coactivator CTNNB1 accumulates and, in turn, replaces the transcriptional repressor associated with TCF1. Interaction with CTNNB1 results in transactivation of TCF1 target genes. Deletion of TCF1 causes massive apoptosis of double positive thymocyte, suggesting that TCF1 is required for thymocyte survival during T cell development. In addition to its function in thymus, TCF1 promotes T cell differentiation to Th2 cells in the periphery through transcriptional activation of GATA3.
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途径
- WNT signaling
抗原
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