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H2AFX 抗体 (pSer139)

This anti-H2AFX antibody is a 小鼠 单克隆 antibody detecting H2AFX in BCA. Suitable for 人 和 小鼠.
产品编号 ABIN2666075
发货至: 中国

Quick Overview for H2AFX 抗体 (pSer139) (ABIN2666075)

抗原

See all H2AFX 抗体
H2AFX (H2A Histone Family, Member X (H2AFX))

适用

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人, 小鼠

宿主

  • 156
  • 18
  • 2
小鼠

克隆类型

  • 127
  • 49
单克隆

标记

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This H2AFX antibody is un-conjugated

应用范围

  • 138
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Biochemical Assay (BCA)

克隆位点

2F3
  • 抗原表位

    • 36
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    pSer139

    纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store between 2°C and 8°C.
  • 抗原

    H2AFX (H2A Histone Family, Member X (H2AFX))

    别名

    H2A.X

    背景

    H2A.X is a 14 kD basal histone and a member of the H2 histone family. This nuclear protein is synthesized in the G1 and S phase of the cell cycle and is known to be important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 after double-stranded DNA breaks. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting and immunofluorescence.

    途径

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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