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CD44 抗体

CD44 适用: 人, 小鼠 FACS, IF 宿主: 大鼠 Monoclonal IM7 unconjugated
产品编号 ABIN2665996
发货至: 中国
  • 抗原 See all CD44 抗体
    CD44
    适用
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    人, 小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CD44 antibody is un-conjugated
    应用范围
    • 277
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    品牌
    Ultra-LEAF™
    交叉反应
    Chimpanzee, Baboon, Cynomolgus, 猕猴, Squirrel Monkey (Saimiri spec.), 马, 牛, 猪, 犬, 猫
    纯化方法
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    克隆位点
    IM7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD44 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    储存液
    Azide free
    注意事项
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD44
    别名
    CD44 (CD44 产品)
    背景
    CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
    途径
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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