TIM3 抗体
-
- 抗原 See all TIM3 (TIM 3) 抗体
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TIM3 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS)
- 品牌
- Ultra-LEAF™
- 交叉反应
- 猕猴
- 纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
-
Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- 克隆位点
- F38-2E2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TIM 3 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 储存液
- Azide free
- 注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- 抗原
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- CD366 (TIM 3 产品)
- 物质类
- Virus
- 背景
- CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
-