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Notch1 抗体

This 仓鼠 单克隆 anti-Notch1 antibody (Clone HMN1-12) specifically detects Notch1 in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2665299
发货至: 中国
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Quick Overview for Notch1 抗体 (ABIN2665299)

抗原

See all Notch1 (NOTCH1) 抗体
Notch1 (NOTCH1) (Notch 1 (NOTCH1))

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This Notch1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

HMN1-12
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Notch1 (NOTCH1) (Notch 1 (NOTCH1))

    别名

    Notch 1

    背景

    The Notch receptors are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the greatest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. Notch 3 is primarily expressed in adult arterial smooth muscle cells. Notch 3 gene mutation can cause CADASIL, an inherited early stroke syndrome.

    途径

    Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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