电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MUC1 抗体

MUC1 适用: 人 ICFC 宿主: 小鼠 Monoclonal 16A unconjugated
产品编号 ABIN2664412
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
    适用
    • 252
    • 58
    • 31
    • 12
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 168
    • 95
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 147
    • 113
    • 7
    单克隆
    标记
    • 154
    • 20
    • 13
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MUC1 antibody is un-conjugated
    应用范围
    • 134
    • 124
    • 103
    • 91
    • 72
    • 46
    • 24
    • 24
    • 20
    • 19
    • 16
    • 14
    • 13
    • 13
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    16A
    亚型
    IgG1 lambda
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    CD227 (MUC1 产品)
    背景
    Mucin-1 (MUC-1), cell surface associated or polymorphic epithelia mucin, is a 500-1000 kD proteoglycan expressed by activated T cells, mucosal epithelial cells, and aberrantly expressed on most breast cancers. In normal cells, CD227 is heavily glycosylated, whereas in cancerous cells, the glycosylation is incomplete and premature sialation is also observed. The protein is anchored to the apical surface of the epithelial cell and functions as a lubricant to keep the cell hydrated and to protect against pathogens. It can also function as a signaling molecule by forming a MUC-1/SOS1/GrB2 complex. MUC-1 can interact with cancer antigens such as Her2/neu.
    途径
    Negative Regulation of intrinsic apoptotic Signaling
You are here:
客服