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IGF1R 抗体

IGF1R 适用: 人 FACS 宿主: 小鼠 Monoclonal 1H7-CD221 unconjugated
产品编号 ABIN2664409
发货至: 中国
  • 抗原 See all IGF1R 抗体
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IGF1R antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    1H7-CD221
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IGF1R Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    别名
    CD221 (IGF1R 产品)
    背景
    CD221, also known as insulin-like growth factor 1 receptor (IGF1R), is a 135 kD transmembrane receptor. It is widely expressed on lymphoid and myeloid cells as well as non-haematopoietic cells. CD221 is a tyrosine kinase receptor and the ligands for CD221 are insulin-like growth factor 1 and 2 (IGF-1 and IGF-2), the polypeptide hormones similar in molecular structure to insulin. IGF-1/2 binding activates downstream PI3K and MAPK pathways and plays an important role in cell growth. Recent studies reveal its function of recruiting immune cells during tissue repair.
    途径
    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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