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CCR3 抗体

CCR3 适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal 5E8 unconjugated
产品编号 ABIN2664333
发货至: 中国
  • 抗原 See all CCR3 抗体
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
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    This CCR3 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    5E8
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CCR3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CD193 (CCR3 产品)
    背景
    CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
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