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CCR3 抗体

This anti-CCR3 antibody is a 小鼠 单克隆 antibody detecting CCR3 in FACS, IHC 和 IF. Suitable for 人.
产品编号 ABIN2664333
发货至: 中国

Quick Overview for CCR3 抗体 (ABIN2664333)

抗原

See all CCR3 抗体
CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

适用

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宿主

  • 64
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小鼠

克隆类型

  • 65
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  • 1
单克隆

标记

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This CCR3 antibody is un-conjugated

应用范围

  • 53
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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

5E8
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

    别名

    CD193

    背景

    CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
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