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C5AR1 抗体

C5AR1 适用: 人 FACS, IF, IP 宿主: 小鼠 Monoclonal C17-5 unconjugated
产品编号 ABIN2664088
发货至: 中国
  • 抗原 See all C5AR1 抗体
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    适用
    • 103
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    • 5
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    宿主
    • 75
    • 24
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    小鼠
    克隆类型
    • 77
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    单克隆
    标记
    • 52
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    This C5AR1 antibody is un-conjugated
    应用范围
    • 65
    • 55
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    • 11
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    C17-5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product C5AR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    别名
    C5a/C5a (C5AR1 产品)
    别名
    C5A antibody, C5AR antibody, C5R1 antibody, CD88 antibody, C5aR antibody, C5r1 antibody, Cd88 antibody, D7Msu1 antibody, GPR77 antibody, complement C5a receptor 1 antibody, complement component 5a receptor 1 antibody, C5AR1 antibody, C5ar1 antibody, c5ar1 antibody
    背景
    C5, complement component 5, is a protein involved in the complement system. It is cleaved into C5a and C5b by the C3/C5 convertase. The smaller fragment C5a is an anaphylatoxin and is released into the fluid surroundings. C5a is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis). C5a contains 74 amino acids and is rapidly metabolised by a serum enzyme, carboxypeptidase B to a 73 amino acid form, C5a des-Arg. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex.
    途径
    Complement System
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