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Integrin beta 2 抗体 (FITC)

This FITC-conjugated 大鼠 单克隆 anti-Integrin beta 2 antibody (Clone M18-2) specifically detects Integrin beta 2 in IHC, ELISA, Neut, ICFC 和 CyTOF. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2661540
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Integrin beta 2 抗体 (FITC) (ABIN2661540)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Integrin beta 2 antibody is conjugated to FITC

应用范围

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Immunohistochemistry (IHC), ELISA, Neutralization (Neut), Intracellular Flow Cytometry (ICFC), Mass Cytometry (CyTOF)

克隆位点

M18-2
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    CD18

    背景

    CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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