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IL2 Receptor beta 抗体 (Biotin)

IL2RB 适用: 小鼠 FACS, IHC, BR 宿主: 大鼠 Monoclonal 5H4 Biotin
产品编号 ABIN2660928
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 抗体
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    适用
    • 92
    • 77
    • 16
    • 5
    • 1
    小鼠
    宿主
    • 85
    • 25
    • 21
    大鼠
    克隆类型
    • 86
    • 44
    • 1
    单克隆
    标记
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    This IL2 Receptor beta antibody is conjugated to Biotin
    应用范围
    • 73
    • 55
    • 38
    • 26
    • 26
    • 17
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    • 10
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Blocking Reagent (BR)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    5H4
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL2RB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    CD122 (IL2RB 产品)
    别名
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    物质类
    Chemical
    背景
    CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit(CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
    途径
    JAK/STAT Signaling, Growth Factor Binding
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