CCR3 抗体 (PerCP-Cy5.5)
Quick Overview for CCR3 抗体 (PerCP-Cy5.5) (ABIN2660014)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
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亚型
 - IgG2b kappa
 
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应用备注
 - Optimal working dilution should be determined by the investigator.
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限制
 - 仅限研究用
 
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缓冲液
 - Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from prolonged exposure to light. Do not freeze.
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储存条件
 - 4 °C
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储存方法
 - The antibody solution should be stored undiluted between 2°C and 8°C.
 
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
 - CD193
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背景
 - CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
 
抗原
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