CSF1R 抗体 (PE-Cy7)
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- 抗原 See all CSF1R 抗体
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CSF1R antibody is conjugated to PE-Cy7
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
- 克隆位点
- 9-4D2-1E4
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CSF1R Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
- 别名
- CD115 (CSF1R 产品)
- 背景
- CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitinylation of intracellular residues. The natural ligands of CD115 include M-CSF and IL-34. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, plasmacytoid and conventional dendritic cells, and osteoclasts.
- 途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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