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CTLA4 抗体 (APC)

CTLA4 适用: 小鼠 WB, IHC, Neut, ICFC, ELISA (Capture) 宿主: 仓鼠 Monoclonal UC10-4B9 APC
产品编号 ABIN2658496
发货至: 中国
  • 抗原 See all CTLA4 抗体
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    适用
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    小鼠
    宿主
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    仓鼠
    克隆类型
    • 87
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    单克隆
    标记
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    This CTLA4 antibody is conjugated to APC
    应用范围
    • 87
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    Western Blotting (WB), Immunohistochemistry (IHC), Neutralization (Neut), Intracellular Flow Cytometry (ICFC), ELISA (Capture)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    UC10-4B9
    亚型
    IgG
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CD152 (CTLA4 产品)
    背景
    CD152, also known as CTLA-4 or Ly-56, is a 33 kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.
    途径
    Cancer Immune Checkpoints
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