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Integrin beta 3 抗体 (APC)

ITGB3 适用: 小鼠, 大鼠 FACS 宿主: 仓鼠 Monoclonal 2C9-G2 (HMbeta3-1) APC
产品编号 ABIN2658258
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    小鼠, 大鼠
    宿主
    • 120
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    仓鼠
    克隆类型
    • 115
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    单克隆
    标记
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    This Integrin beta 3 antibody is conjugated to APC
    应用范围
    • 122
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    2C9-G2 (HMbeta3-1)
    亚型
    IgG
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    CD61 (ITGB3 产品)
    背景
    CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1).
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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